compound introduction
SGX-523是一种选择性的Met抑制剂，IC50为4 nM，对BRAFV599E， c-Raf， Abl和p38α无抑制活性。A Met inhibitor SGX-523 is a selective Met inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-Raf, Abl and p38α. A Met inhibitor
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SGX-523
CAS number：1022150-57-7 molecular formula：C18H13N7S
overview
Specs
| Chinese alias | - | ||
| English alias | 6-((6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)quinoline | AKOS025117577 | NCGC00263163-01 | SMR004701349 | Q27088796 | Quinoline, 6-[[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]-;Quinoline, 6-[[6-(1- | ||
| CAS number | 1022150-57-7 | molecular formula | C18H13N7S |
| molecular weight | 359.42 g/mol | Exact mass | - |
| PSA | 99.100 Ų | logp | 2.4 |
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