CAS number：714971-09-2 molecular formula：C27H27FN8O3
AC480 (BMS-599626)是 HER1和HER2选择性高效抑制剂，IC50分别为20 nM和30 nM，比针对VEGFR2，c-Kit，Lck，MET的抑制性强100倍以上。 AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc.
| Chinese alias | [4-[[1-(3-氟苄基)-1H-吲唑-5-基]氨基]-5-甲基吡咯并[2,1-f][1,2,4]三嗪-6-基]氨基甲酸(S)-吗啉-3-基甲酯 | ||
| English alias | UNII-04201GDN4R | BMS 599626 | Carbamic acid, N-(4-((1-((3-fluorophenyl)methyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo(2,1-F)(1,2,4)triazin-6-yl)-, (3S)-3-morpholinylmethyl ester | Mometasona [Spanish] | NCGC00346483-05 | NCGC00346483-11 | UCB-L-060 | [(3 | ||
| CAS number | 714971-09-2 | molecular formula | C27H27FN8O3 |
| molecular weight | 530.55 g/mol | Exact mass | - |
| PSA | 120.000 Ų | logp | 2.8 |
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