CAS number：2244775-31-1 molecular formula：C22H27ClN8O3S
Information F-1 is a potent dual inhibitor of ALK and ROS1 that suppresses phospho-ALK and its relative downstream signaling pathways with IC50 of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.
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| English alias | - | ||
| CAS number | 2244775-31-1 | molecular formula | C22H27ClN8O3S |
| molecular weight | 519.02 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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