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Ningetinib

CAS number:1394820-69-9    molecular formula:C31H29FN4O5

overview

compound introduction

Information Ningetinib (CT-053, DE-120, CT053PTSA) is a potent, orally bioavailable inhibitor oftyrosine kinasewith IC50 of 6.7 nM, 1.9 nM and Targets Axl (Cell-free assay); VEGFR2 (Cell-free assay); c-Met (Cell-free assay) 1.0 nM; 1.9 nM; 6.7 nM

Specs

Chinese alias-
English aliasN-(3-Fluoro-4-((7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl)oxy)phenyl)-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide | NSC781652 | NSC-781652 | CT053PTSA | EX-A1889 | N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)pheny
CAS number1394820-69-9molecular formulaC31H29FN4O5
molecular weight556.58 g/molExact mass-
PSA104.000 Ųlogp4.8

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