Information Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selectivetyrosine kinaseinhibitor ofEGFR,HER2andHER4with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity. Targets EGFR (Cell-free assay); HER4 (Cell-free assay); HER2 (Cell-free assay) 1.48 nM; 2.49 nM; 7.15 nM
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Epertinib hydrochloride
CAS number:2071195-74-7 molecular formula:C30H28Cl2FN5O3
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| Chinese alias | - | ||
| English alias | Epertinib HCl | S-222611 hydrochloride | S-222611 HCl | ||
| CAS number | 2071195-74-7 | molecular formula | C30H28Cl2FN5O3 |
| molecular weight | 596.48 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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