BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11 nM. Appearance:Solid IC50& Target:IC50: 11 nM (FLT3) In Vitro:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11nM. Phosphorylation of all FLT3-WT, FLT3-IDT, and FLT3-D835Y are inhibited by BPR1J-097 Hydrochloride at a concentration as low as 10 nM. BPR1J-097 Hydrochloride suppresses th In Vivo:After i.v. administration of mice with BPR1J-097 Hydrochloride at two cycles of 10 or 25mg/kg, a clear dose-dependent anti-tumour effect is observed. Tumours in mice treated with BPR1J-097 Hydrochloride (25mg/kg per day) stop growing. BPR1J-097 Hydrochl Biological Activity:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11u2009nM.
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BPR1J-097 Hydrochloride
CAS number：1327167-19-0(free base) molecular formula：C27H29ClN6O3S
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| Chinese alias | BPR1J-097 盐酸盐 | ||
| English alias | - | ||
| CAS number | 1327167-19-0(free base) | molecular formula | C27H29ClN6O3S |
| molecular weight | 553.08 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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