Dihexa (PNB-0408),一种寡肽试剂,是一种具有口服活性,血脑屏障可渗透性的血管紧张素 IV 类似物。Dihexa 高亲和力结合肝细胞生长因子(HGF),Kd值为 65 pM,并增强了其对受体 c-Met 的活性。Dihexa 在动物模型中显示出优异的抗精神病活性以及改善认知功能。Dihexa 具有研究阿尔茨海默症的潜力。
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Dihexa
CAS number:1401708-83-5 molecular formula:C27H44N4O5
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1401708-83-5 | molecular formula | C27H44N4O5 |
| molecular weight | 504.66 g/mol | Exact mass | ≥98% |
| PSA | 151.000 Ų | logp | 2.300 |
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