compound introduction
NSC194598 是 p53 DNA 结合抑制剂，在体外和体内抑制 p53 序列特异性 DNA 结合的IC50值分别为 180 nM 和 2-40 μM。NSC194598干扰人甲状腺髓样癌 TT 细胞中突变RET基因的转录激活。NSC194598 可用于放射和化疗对正常组织的急性毒性的研究。
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Indeno[1,2,3-de]quinazoline, 2-(1-piperidinylmethyl)-, 1-oxide
CAS number：5358-76-9 molecular formula：
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 5358-76-9 | molecular formula | |
| molecular weight | 317.400 g/mol | Exact mass | ≥98% |
| PSA | 41.600 Ų | logp | 2.600 |
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