L-778123是一种双FPTase和GGPTase-I抑制剂,ic50分别为2 nM和98 nM。 L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC50s of 2 nM and 98 nM respectively.
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L-778123
CAS number:183499-57-2 molecular formula:C22H20ClN5O
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compound introduction
Specs
| Chinese alias | 4-((5-((4-(3-氯苯基)-3-氧代哌嗪-1-基)甲基)-1H-咪唑-1-基)甲基)苯甲腈 | ||
| English alias | 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | ||
| CAS number | 183499-57-2 | molecular formula | C22H20ClN5O |
| molecular weight | 405.88 g/mol | Exact mass | - |
| PSA | 65.200 Ų | logp | 2.700 |
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