N-甲基原卟啉IX是诸如叶绿素,血红素和细胞色素c的修复基团的生物前体的衍生物。N-甲基原卟啉IX被分类为过渡态类似物。原卟啉IX铁螯合酶被N-甲基原卟啉IX(K | i | = 10 nM)有效抑制。N-甲基原卟啉IX在血红素生物合成途径的末端有效地产生了阻断作用。 N-Methyl Protoporphyrin IX is a derivative of a biological precursor to prosthetic groups such as chlorophyll, heme, and cytochrome c. N-Methyl Protoporphyrin IX is classified as a transition state analog. Protoporphyrin IX ferrochelatase is potently inhibited by N-Methyl Protoporphyrin IX (K|i|= 10 nM). N-Methyl Protoporphyrin IX effectively creates a blockade at the terminal step of the heme biosynthetic pathway.
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N-Methyl Protoporphyrin IX
CAS number:79236-56-9 molecular formula:C₃₅H₃₆N₄O₄
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17,22-pentamethyl-23H-porphyrin-2-yl]propanoic acid | 3-[(5Z,10Z,14Z,19Z)-18-(2-carboxyethyl)-3,8,13,17,23-pentamethyl-7,12-divinyl-21H-porphyrin-2-yl]propanoic acid | N-Methylprotoporphyrin IX | NMPP | 21H, | ||
| CAS number | 79236-56-9 | molecular formula | C₃₅H₃₆N₄O₄ |
| molecular weight | 576.69 g/mol | Exact mass | ≥95% |
| PSA | 121.000 Ų | logp | 4.600 |
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