compound introduction
二肽基肽酶IV是一种淋巴细胞表面抗原，在T细胞活化过程中增加，也在其他组织中表达，如胎盘、肾脏等。它是一种非典型丝氨酸蛋白酶，与多种生物学功能有关，包括糖尿病、类风湿性关节炎、T细胞活化、细胞间粘附，最近还与HIV感染有关。 活性：一个单位定义为在25°C、pH 7.8下每分钟水解一umole H-Gly-Pro-pNA的酶量。 Dipeptidyl Peptidase IV is a lymphocyte cell surface antigen which is increased during T-cell activation and is also expressed in other tissues, such as placenta, kidney, etc. It is an atypical serine protease which has been implicated in a variety of biological functions including diabetes, rheumatoid arthritis, T-cell activation, cell-to-cell adhesion, and recently in HIV infection. Activity: One unit is defined as the amount of enzyme that hydrolyzes one umole of H-Gly-Pro-pNA per minute at 25°C, pH 7.8.
