compound introduction
Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function IGF2R is a multifunctional receptor with binding sites for a variety of ligands, including insulin-like growth factor II (IGF2; 147470), retinoic acid (RA), TGF-β (TGFB1; 190180), urokinase-type plasminogen activator receptor (UPAR, or PLAUR; 173391) and mannose 6-phosphate (M6P), a modification characteristic of a lysosomal enzyme. IGF2R plays a major role in controlling IGF signaling by directing IGF2 to lysosomes, targeting lysosomal enzymes to lysosomes, and recycling lysosomal enzymes from the plasma membrane
