beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens , with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum , with an IC 50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) In Vitro beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Plasmodium
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beta-Mangostin
CAS number：20931-37-7 molecular formula：C25H28O6
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| Chinese alias | β-山竹素 | ||
| English alias | 1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one | CHEBI:175406 | 9H-Xanthen-9-one, 1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-butenyl)- | 1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one | YRKKJHJIWCRNCW | ||
| CAS number | 20931-37-7 | molecular formula | C25H28O6 |
| molecular weight | 424.49 g/mol | Exact mass | ≥99% |
| PSA | 85.200 Ų | logp | 6.600 |
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