compound introduction
Bavachalcone 是有效的凋亡 (apoptosis) 诱导剂。Bavachalcone 通过促进 HepG2 细胞的自噬 (autophagy) 和凋亡发挥抗癌活性。Bavachalcone 通过 NF-κB 通路发挥抗神经炎症和抗抑郁的作用。Bavachalcone 通过干扰 ERK 和 Akt 信号通路以及 c-Fos 和 NFATc1 的表达抑制破骨细胞的发生。Bavachalcone 在体外对杆状病毒表达的 BACE-1 有显著的抑制作用。 Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of c-Fos and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro.
