compound introduction
KKL-40 是一种靶向反式转录过程的小分子抑制剂，有效抑制甲氧西林敏感和耐药的金黄色葡萄球菌 (S. aureus) 以及其他革兰氏阳性病原体（包括耐万古霉素的屎肠球菌、枯草芽孢杆菌和化脓性链球菌）。KKL-40 与人类抗菌肽 LL-37 协同作用抑制金黄色葡萄球菌，但不与其他抗生素如达托霉素、卡那霉素或红霉素产生协同效应。反式转录是重新编码的一种极端形式，KKL-40 抑制反式转录，但对 HeLa 细胞无毒。
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N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)-3-(trifluoromethyl)benzamide
CAS number：865285-47-8 molecular formula：C16H9F4N3O2
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 865285-47-8 | molecular formula | C16H9F4N3O2 |
| molecular weight | 351.250 g/mol | Exact mass | - |
| PSA | 68.000 Ų | logp | 3.600 |
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