Purfalcamine 是一种具有口服活性,选择性的恶性疟原虫钙依赖性蛋白激酶 1 (PfCDPK1) 抑制剂,IC50为 17 nM,EC50为 230 nM。Purfalcamine 具有抗疟疾活性,可以引起疟原虫在裂殖体阶段的发育停滞。
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Purfalcamine
CAS number:1038620-68-6 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1038620-68-6 | molecular formula | |
| molecular weight | 528.600 g/mol | Exact mass | ≥99% |
| PSA | 114.000 Ų | logp | 4.700 |
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