compound introduction
TAK-242 是一种有效的 TLR4 抑制剂，选择性抑制 TLR4 调节的细胞因子和 NO 产生。 TAK-242 is a cell-permeable compound that selectively binds to Cys747 of TLR4 and selectively disrupts its interaction with adaptor molecules TIRAP and TRAM.
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TAK-242
CAS number：243984-11-4 molecular formula：C15H17ClFNO4S
overview
Specs
| Chinese alias | 瑞沙托维 | TLR4 抑制剂 | 乙基-(6R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯-1-羧酸乙酯 | ||
| English alias | AC-31498 | CLI-095 | Q27088534 | s7455 | BDBM50155929 | CLI-095TAK-242 | TAK-242 (Resatorvid) | Resatorvid; TAK-242 | A904215 | Resatorvid (tak-242) | GTPL9036 | Resatorvid [INN] | EX-A3158 | ethyl (6r)-6-[n-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-e | ||
| CAS number | 243984-11-4 | molecular formula | C15H17ClFNO4S |
| molecular weight | 361.82 g/mol | Exact mass | - |
| PSA | 80.900 Ų | logp | 3 |
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