GDC-0349 是一种有效的,ATP竞争性的选择性 mTOR 抑制剂,Ki 值为 3.8 nM。GDC-0349 抑制 mTORC1 和 mTORC2 复合体。 Product description GDC-0349 is a potent and selective ATP-competitive mTOR inhibitor with a Ki of 3.8 nM. GDC-0349 inhibits of both mTORC1 and mTORC2 complexes.
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GDC-0349
CAS number:1207360-89-1 molecular formula:C24H32N6O3
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| Chinese alias | - | ||
| English alias | 579255I6O9 | EX-A2248 | Q27261488 | UNII-579255I6O9 | MLS006011173 | NSC780878 | NSC-780878 | (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea | HY-15248 | NSC771532 | NSC-771532 | BDBM5042 | ||
| CAS number | 1207360-89-1 | molecular formula | C24H32N6O3 |
| molecular weight | 452.55 g/mol | Exact mass | ≥99% |
| PSA | 91.900 Ų | logp | 1.400 |
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