CAS number：96027-74-6 molecular formula：C23H26ClI2NO3
去乙基胺碘酮盐酸盐是 Amiodarone 的主要活性代谢产物。Desethylamiodarone hydrochloride 是由 CYP3A 同工酶形成的。Amiodarone 是一种抗心律失常药，用于抑制 ATP 敏感性钾通道，IC50 为 19.1 μM。 Desethylamiodarone hydrochloride is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM。
| Chinese alias | (2-丁基苯并呋喃-3-基)(4-(2-(乙基氨基)乙氧基)-3,5-二碘苯基)甲酮盐酸盐 | ||
| English alias | N-desethylamiodarone hydrochloride | (2-butylbenzofuran-3-yl)(4-(2-(ethylamino)ethoxy)-3,5-diiodophenyl)methanone hydrochloride | LB 33020 hydrochloride | ||
| CAS number | 96027-74-6 | molecular formula | C23H26ClI2NO3 |
| molecular weight | 653.72 g/mol | Exact mass | ≥98% |
| PSA | 51.500 Ų | logp | - |
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