R1487 Hydrochloride 是强效、选择性的 p38α 抑制剂,其对 p38α 和 p38β 的 Kd 值分别为 0.2 nM 和 29 nM。
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R1487 Hydrochloride
CAS number:449808-64-4 molecular formula:C19H19ClF2N4O3
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compound introduction
Specs
| Chinese alias | R1487 盐酸盐 | ||
| English alias | R1487 HCl | EX-A670 | FT-0700307 | SCHEMBL20582726 | UNII-E89N7YW9YQ | 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, trihydrate, (2S-(2alpha,5alpha,6beta(S*)))- | 6-(2,4-Difluorophenoxy)-8-methyl-2- | ||
| CAS number | 449808-64-4 | molecular formula | C19H19ClF2N4O3 |
| molecular weight | 424.83 g/mol | Exact mass | ≥98% |
| PSA | 76.600 Ų | logp | - |
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