AT9283是多靶点抑制剂,对Bcr-Abl(T3151),Jak2,Jak3,aurora A和B的IC50分别为4,1.2,1.1,3 nM和3 nM。 AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl(T3151), JAK2 and JAK3, Aurora A and Aurora B, respectively. An inhibitor of Aurora A, Aurora B, JAK3, JAK2, and c-Abl
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AT9283
CAS number:896466-04-9 molecular formula:C19H23N7O2
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| Chinese alias | - | ||
| English alias | NSC799339 | NSC-799339 | AKOS016006006 | 1-cyclopropyl-3-[(3Z)-3-[5-(morpholin-4-ylmethyl)benzimidazol-2-ylidene]-1,2-dihydropyrazol-4-yl]urea | AT 9283 [WHO-DD] | HMS3673I15 | 35R | A900407 | HMS3244P09 | TIAMULIN [INN] | 1-cyclopropyl-3-[3-(5-morpholin- | ||
| CAS number | 896466-04-9 | molecular formula | C19H23N7O2 |
| molecular weight | 381.43 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 0.5 |
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