compound introduction
E3 ligase ligand-linker conjugate, Thalidomide-O-PEG4-Propargyl, is synthesized compound that incorporates the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
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Thalidomide-O-PEG4-Propargyl
CAS number：2098799-77-8 molecular formula：C24H28N2O9
overview
Specs
| Chinese alias | 4-((3,6,9,12-四氧杂十五碳-14-炔-1-基)氧基)-2-(2,6-二氧代哌啶-3-基)异吲哚啉-1,3-二酮 | ||
| English alias | Thalidomide-O-PEG4-Propargyl | 4-((3,6,9,12-Tetraoxapentadec-14-yn-1-yl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-4-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]isoindole-1,3-dione | ||
| CAS number | 2098799-77-8 | molecular formula | C24H28N2O9 |
| molecular weight | 488.50 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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