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HaloPROTAC-E

CAS number:2365478-58-4    molecular formula:C39H56ClN5O8S

overview

compound introduction

HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34 , with a DC 50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1 , and ATG14). Form:Oil

Specs

Chinese alias-
English alias-
CAS number2365478-58-4molecular formulaC39H56ClN5O8S
molecular weight790.4 g/molExact mass-
PSA-logp-

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