Cilengitide是一种有效的integrin(整合素)抑制剂,作用于αvβ3受体和αvβ5受体,IC50分别为4.1 nM和79 nM,比作用于gpIIbIIIa选择性高10倍左右。 Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa.
Cilengitide acetate
CAS number:188968-51-6(free base) molecular formula:C27H40N8O7(free base)
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 188968-51-6(free base) | molecular formula | C27H40N8O7(free base) |
| molecular weight | 588.66(free base) g/ | Exact mass | ≥98% |
| PSA | 238.000 Ų | logp | -1.000 |
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