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Indomethacin-d4

CAS number:87377-08-0    molecular formula:C19H12D4ClNO4

overview

compound introduction

Indomethacin-d4是 Indomethacin 的一种氘代化合物。 Indomethacin 是一种有效的,可透过血脑屏障的,非选择性的COX1和COX2抑制剂,在 CHO 细胞中,对人COX-1和COX-2的IC50值分别为 18 nM 和 26 nM。Indomethacin 通过干扰溶酶体的正常功能来破坏自噬流 (autophagic flux)。

Specs

Chinese alias-
English alias-
CAS number87377-08-0molecular formulaC19H12D4ClNO4
molecular weight361.81 g/molExact mass≥99%
PSA68.500 Ųlogp4.300

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