compound introduction
Lotamilast (RVT-501; E6005) 是选择性的磷酸二酯酶4 (PDE4) 抑制剂，IC50 值为2.8 nM。 Lotamilast (RVT-501, E6005) is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50 of 2.8 nM.
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e-6005
CAS number：947620-48-6 molecular formula：C26H24N4O5
overview
Specs
| Chinese alias | 4-[[[3-[6,7-二甲氧基-2-(甲基氨基)-4-喹唑啉基]苯基]氨基]羰基]-苯甲酸甲酯 | ||
| English alias | (Methyl 4-(((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl(amino)carbonyl)benzoate | EX-A1382 | SPIUTQOUKAMGCX-UHFFFAOYSA-N | AS-52366 | DB12776 | MFCD28502071 | RVT-501 | AC-35466 | Methyl 4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phen | ||
| CAS number | 947620-48-6 | molecular formula | C26H24N4O5 |
| molecular weight | 472.501 g/mol | Exact mass | ≥96% |
| PSA | 112.000 Ų | logp | 4.2 |
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