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Recombinant Human CD90/Thy1 Protein

CAS number:unknown    molecular formula:

overview

compound introduction

Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining Description: CD90, also known as Thy1, is an approximately 25-35 kDa glycoprotein that mediates cellular adhesion and exerts wide-ranging effects in different tissues. CD90 is expressed on hematopoietic progenitor cells, neurons, and activated vascular endothelial cells. Its species-specific expression in lymphoid cells allows its use as a thymocyte and pan T cell marker in mice but not in humans. CD90 can form dimers and higher-order multimers. It binds to heparin, the proteoglycan Syndecan-4, and Integrins alpha M beta 2, alpha V beta 3, and alpha V beta 5. Through these interactions, CD90 inhibits neurite outgrowth, promotes astrocyte adhesion, mediates the adhesion and extravasation of leukocytes and melanoma cells, supports Thrombospondin-1-induced disassembly of fibroblast focal adhesions, and inhibits the activation of latent TGF-beta 1, myofibroblast differentiation, and lung fibrosis. Human Thy-1 shares 63% and 66% amino acid similarity with mouse and rat homologs.

Specs

Chinese aliasThy1 | 重组人CD90/Thy1蛋白 | 重组人 CD90/Thy1 蛋白
English aliasCD90 antigen | CD90 | CDw90 | FLJ33325 | Thy-1 antigen | Thy-1 cell surface antigen | thy-1 membrane glycoprotein | Thy-1 T-cell antigen | Thy1 | CD7 antibody | CD90 antibody | CD90 antigen antibody | CDw90 antibody | FLJ33325 antibody | MGC128895 antibod
CAS numberunknownmolecular formula
molecular weight-Exact mass无动物源
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