Product introduction： MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates). Features of MPBH: • Reactive groups: maleimide andhydrazide • Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups • Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable) • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages • Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates • Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups • Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups Product References: Crosslinker Application Guide -- search for recent literature references for this product • Reactive Moiety: Amine,Hydrazide,Maleimide • Crosslinker Type: Heterobifunctional • Form: Powder • Spacer: Medium(10 to 30 Å) • Labeling Method: Chemical Labeling • Spacer Arm Length: 17.9 Å
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
MPBH(4-(4-N-maleimidophenyl)butyric acid hydrazide)
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | MPBH(4-(4-N-马来酰亚胺苯基)丁酸酰肼) | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | |
| molecular weight | 309.75 g/mol | Exact mass | - |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
