DBCO-PEG4-VC-PAB-DMEA-PNU-159682，一种用于 ADC 的活性分子-偶联物，由 ADC 接头 DBCO-PEG4-VC-PAB 和有效的 ADC 细胞毒素 DMEA-PNU-159682 组成。 DMEA-PNU-159682 包括来自肝微粒体代谢产物的新霉素 (MMDX) 和 ADC 细胞毒素 PNU-159682。DBCO-PEG4-VC-PAB-DMEA-PNU-159682 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) DBCO-PEG4-VC-PAB-DMEA-PNU-159682， An active molecule conjugate for ADC, consisting of ADC linker DBCO-PEG4-VC-PAB and effective ADC cytotoxic DMEA-PNU-159682. DMEA-PNU-159682 includes neomycin (MMDX) derived from liver microsomal metabolites and ADC cytotoxic PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent. It contains DBCO groups and can undergo strain induced acetylene azide cycloaddition reaction (SPAAC) with molecules containing Azide groups.
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DBCO-PEG4-VC-PAB-DMEA-PNU-159682
CAS number：2259318-56-2 molecular formula：C86H106N10O26
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2259318-56-2 | molecular formula | C86H106N10O26 |
| molecular weight | 1695.81 g/mol | Exact mass | ≥84% |
| PSA | - | logp | - |
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