Azido-PEG6-alcohol 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。Azido-PEG6-alcohol 也是一种不可降解 (non-cleavable) 的含 6 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Azido-PEG6-alcohol 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC) Azido-PEG6-alcohol is a PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules. Azido-PEG6-alcohol is also a non-cleavable 6-unit PEG ADC linker that can be used to synthesize antiboy-conjugated active molecules (ADCs). Azido-PEG6-alcohol is a click chemical. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo cyclic tension-driven acetylene-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.
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Azido-PEG6-alcohol
CAS number：86770-69-6 molecular formula：C12H25N3O6
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compound introduction
Specs
| Chinese alias | 7-叠氮基-3,6,9,12,15-五氧杂十七烷-1-醇 | ||
| English alias | 17-azido-1-hydroxy-3,6,9,12,15-pentaoxaheptadecane | 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-azido- | Azido-PEG6 | C70120 | 17-Azido-3,6,9,12,15-pentaoxa-1-heptadecanol | BP-20602 | 17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol | 2-[2-(2-{2-[2-(2-Azido-eth | ||
| CAS number | 86770-69-6 | molecular formula | C12H25N3O6 |
| molecular weight | 307.34 g/mol | Exact mass | ≥97% |
| PSA | 80.700 Ų | logp | -0.300 |
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