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CAY10502

CAS number:888320-29-4    molecular formula:C30H37NO7

overview

compound introduction

CAY10502是一种有效的钙依赖型胞质PLA2(cPLA2α)抑制剂,对从人血小板中纯化的酶的IC50值为4.3 nM。抑制花生四烯酸从A23187刺激或TPA刺激的人血小板中的动员,其IC50值分别为570和0.9 nM。 CAY10502 is a potent Calcium-dependent cytosolic PLA2 (cPLA2α) inhibitor with an IC50 value of 4.3 nM for the purified enzyme from human platelets. Inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively.

Specs

Chinese alias-
English aliasBDBM50185354 | compound 57 [PMID: 16610804] | HMS3650G20 | HY-116301 | 1-(3-(4-(Decyloxy)phenoxy)-2-oxopropyl)-3-(methoxycarbonyl)-1H-indole-5-carboxylic acid | 1-[3-(4-decoxyphenoxy)-2-oxopropyl]-3-methoxycarbonylindole-5-carboxylic acid | MS-29698 | AKO
CAS number888320-29-4molecular formulaC30H37NO7
molecular weight523.62 g/molExact mass-
PSA104.000 Ųlogp7.400

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