CAS number：203915-59-7 molecular formula：C21H27N3O8S2
MMP抑制剂II是有效的，可逆的，范围广泛的基质金属蛋白酶抑制剂。抑制MMP-1（IC | 50 | = 24 nM），MMP-3（IC | 50 | = 18.4 nM），MMP-7（IC | 50 | = 30 nM）和MMP-9（IC | 50 | = 2.7 nM）。 MMP Inhibitor II is a potent, reversible, broad range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC|50|= 24 nM), MMP-3 (IC|50|= 18.4 nM), MMP-7 (IC|50|= 30 nM), and MMP-9 (IC|50|= 2.7 nM).
| Chinese alias | - | ||
| English alias | NHDDPC | 2-Pyrimidinecarboxamide, hexahydro-N-hydroxy-1,3-bis((4-methoxyphenyl)sulfonyl)-5,5-dimethyl- | DTXSID00174336 | N25 | SCHEMBL7080532 | HY-119423 | mmp inhibitor ii | J-013273 | 1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDIN | ||
| CAS number | 203915-59-7 | molecular formula | C21H27N3O8S2 |
| molecular weight | 513.6 | Exact mass | ≥95% |
| PSA | 159 | logp | 1.8 |
| CAS | 203915-59-7 |
| Wikidata | Q27463655 |
| ChEMBL ID | CHEMBL115727 |
| NSC Number | NSC Number: NSC727630 |
| PubChem CID | 4218 |
| Nikkaji Number | J997.560H |
| Pharos Ligand ID | KZU7MZKHLGT2 |
| DSSTox Substance ID | DTXSID00174336 |
| XLogP3 | XLogP3-AA: 1.8 |
| 复杂性 | 847 |
| Exact Mass | 513.12395718 |
| 形式电荷 | 0 |
| 重原子计数 | 34 |
| Molecular Weight | 513.6 |
| Monoisotopic Mass | 513.12395718 |
| 可旋转键计数 | 7 |
| 氢键供体计数 | 2 |
| 氢键受体计数 | 10 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 159 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 0 |
| 未定义原子手性中心计数 | 0 |
No safety information yet
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