CAS number：191089-59-5 molecular formula：C33H48N2O6
K-7174 是具有口服活性的 proteasome 和 GATA 的抑制剂。K-7174 抑制细胞黏附。K-7174 诱导细胞凋亡。K-7174 具有抗肿瘤活性，可用于癌症的研究。 在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 K-7174 dihydrochloride 通常具有更好的水溶性和稳定性。 K-7174 is an inhibitor of cell adhesion that inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.
| Chinese alias | - | ||
| English alias | 1H-1,4-Diazepine, hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]- | 36376CA57N | 1H-1,4-Diazepine, hexahydro-1,4-bis((4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl)- | UNII-36376CA57N | 1,4-Bis[(4e)-5-(3,4,5-Trimethoxyphenyl)pent-4-En-1-Y | ||
| CAS number | 191089-59-5 | molecular formula | C33H48N2O6 |
| molecular weight | 568.74 g/mol | Exact mass | ≥97% |
| PSA | 61.900 Ų | logp | 6.200 |
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