CAS number：881202-45-5 molecular formula：C21H20N4
JNJ-26854165 (Serdemetan)是一种HDM2泛素连接酶拮抗剂，作用于p53野生型细胞，诱导早期凋亡，在缺乏功能性p53的细胞中，抑制细胞增殖而延迟细胞凋亡。 JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. A p53 activator and HDM2 ubiquitin ligase (MDM2) inhibitor
| Chinese alias | JNJ-26854165（Serdemetan） | ||
| English alias | CCG-264846 | AS-56263 | NCGC00263171-01 | 2-(Furan-2-yl)thiazolidine-4-carboxylicacid | JNJ-26854165 (Serdemetan) | FT-0689750 | N1-(2-(1H-Indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diamine | PBANXRNIXGEHPZ-UHFFFAOYSA-N | JNJ 26854165 | BCP02124 | A86 | ||
| CAS number | 881202-45-5 | molecular formula | C21H20N4 |
| molecular weight | 328.42 g/mol | Exact mass | ≥98% |
| PSA | 52.700 Ų | logp | 4.600 |
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