Palmitic-acid-5-hydroxy-stearic-acid (5-PAHSA) is also referred to as 5-hexadecanoyloxyoctadecanoic acid (IUPAC name). Description Palmitic-acid-5-hydroxy-stearic-acid (5-PAHSA) is also referred to as 5-hexadecanoyloxyoctadecanoic acid (IUPAC name).5-PAHSA is composed of palmitic acid attached to stearic acid and is in the class of branched lipids referred to as fatty acid esters of hydroxy fatty acids (FAHFAs). 5-PAHSA was found at reduced levels in adipose tissue and serum of insulin-resistant mice. Levels were also found to be lower in white adipose tissue and serum of humans. Studies of oral administration of 5-PAHSA to obese, diabetic mice showed improved glucose tolerance. In characterizing the mechanism, it was found that 5-PAHSA stimulates insulin and GLP-1 secretion and also enhances glucose transport and the Glut4 transporter through activation of GPR-120. Application： 5-PAHSA is composed of palmitic acid attached to stearic acid and is in the class of branched lipids referred to as fatty acid esters of hydroxy fatty acids (FAHFAs). 5-PAHSA was found at reduced levels in adipose tissue and serum of insulin-resistant mice. Levels were also found to be lower in white adipose tissue and serum of humans. Studies of oral administration of 5-PAHSA to obese, diabetic mice showed improved glucose tolerance. In characterizing the mechanism, it was found that 5-PAHSA stimulates insulin and GLP-1 secretion and also enhances glucose transport and the Glut4 transporter through activation of GPR-120.
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palmitic-acid-5-hydroxy-stearic-acid
CAS number：1481636-41-2 molecular formula：C34H66O4
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| Chinese alias | - | ||
| English alias | 5-PAHSA | 5-palmitic acid hydroxy stearic acid | 5-hexadecanoyloxyoctadecanoic acid | ||
| CAS number | 1481636-41-2 | molecular formula | C34H66O4 |
| molecular weight | 538.89 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
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5- (oxypalmitoyl) stearic acid formulation solution | 5- (palmitoyloxy) octadecanoic acid
