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AZD9898

CAS number:2042347-69-1    molecular formula:C20H19ClF3N3O4

overview

compound introduction

AZD9898 是一种口服有效的白三烯-C4 合成酶 (LTC4S) 抑制剂,IC50 值为 0.28 nM。AZD9898 减轻GABA 结合和肝毒性信号。AZD9898 可用于哮喘的研究。 AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma.

Specs

Chinese aliasAZD-9898;example 62 [WO2016177845A1]
English aliasAZD-9898;example 62 [WO2016177845A1]
CAS number2042347-69-1molecular formulaC20H19ClF3N3O4
molecular weight457.83 g/molExact mass-
PSA-logp-

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