AZD9898 是一种口服有效的白三烯-C4 合成酶 (LTC4S) 抑制剂,IC50 值为 0.28 nM。AZD9898 减轻GABA 结合和肝毒性信号。AZD9898 可用于哮喘的研究。 AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma.
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AZD9898
CAS number:2042347-69-1 molecular formula:C20H19ClF3N3O4
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| Chinese alias | AZD-9898;example 62 [WO2016177845A1] | ||
| English alias | AZD-9898;example 62 [WO2016177845A1] | ||
| CAS number | 2042347-69-1 | molecular formula | C20H19ClF3N3O4 |
| molecular weight | 457.83 g/mol | Exact mass | - |
| PSA | - | logp | - |
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