Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC 50 of 0.15 μM In Vitro Malic enzyme inhibitor ME1 (ME1; ME1*) (50 μM; 72?hours) shows a significant reduction in total cell numbers. ? Malic enzyme inhibitor ME1 shows a significant reduction in cell viability/metabolic activity in MTS cell. ? Malic enzyme inhibitor ME1 dose-dependently reduces the number of colonies formed by both HCT116 and HT29 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HCT116 and HT29 cell line Concentration: 50 μM Incubation Time: 72 hours Result: Showed a significant reduction in total cell numbers. Form:Solid IC50& Target:IC50: 0.15 μM (Malic enzyme)
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Malic enzyme inhibitor ME1
CAS number：522649-59-8 molecular formula：C20H21N3O3
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| Chinese alias | 苹果酸酶抑制剂ME1 | ||
| English alias | - | ||
| CAS number | 522649-59-8 | molecular formula | C20H21N3O3 |
| molecular weight | 351.40 g/mol | Exact mass | ≥99% |
| PSA | 64.099 Ų | logp | 2.100 |
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