N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC 50 and pK d of 8.73 and 9.3, respectively. In Vitro The mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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N-Desmethyl Pimavanserin
CAS number:639863-77-7 molecular formula:C24H32FN3O2
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| Chinese alias | N-去甲基匹莫范色林 | ||
| English alias | DTXSID601127221 | UNII-CXL6LOR95E | 1-[(4-Fluorophenyl)methyl]-3-[(4-isobutoxyphenyl)methyl]-1-(4-piperidyl)urea | N-Desmethyl-pimavanserin | Urea, N-((4-fluorophenyl)methyl)-N'-((4-(2-methylpropoxy)phenyl)methyl)-N-4-piperidinyl- | N-Desmethyl Pimavanser | ||
| CAS number | 639863-77-7 | molecular formula | C24H32FN3O2 |
| molecular weight | 413.53 g/mol | Exact mass | ≥98% |
| PSA | 53.600 Ų | logp | 4.100 |
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