Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn.. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects . In Vitro Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC 50 value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC 50 value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Moracin O
CAS number：123702-97-6 molecular formula：C19H18O5
overview
compound introduction
Specs
| Chinese alias | 莫拉辛O | ||
| English alias | DTXSID201317614 | 1,3-Benzenediol, 5-[(6R)-5,6-dihydro-6-(1-hydroxy-1-methylethyl)benzo[1,2-b:5,4-b']difuran-2-yl]- | MoracinO | 5-[(6R)-6-(2-hydroxypropan-2-yl)-5,6-dihydrofuro[3,2-f][1]benzofuran-2-yl]benzene-1,3-diol | BDBM50346796 | Moracin O | (-)-Mo | ||
| CAS number | 123702-97-6 | molecular formula | C19H18O5 |
| molecular weight | 326.34 g/mol | Exact mass | ≥99% |
| PSA | 83.100 Ų | logp | 3.300 |
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