compound introduction
LY404039 是一种有效的，选择性的，具有口服活性的 mGluR2 和 mGluR3 激动剂，对重组人 mGluR2 和 mGluR3 的 Ki 分别为 149 nM 和 92 nM，比对其他受体/转运蛋白的抑制性高 100 倍以上。LY404039 具有抗精神病和抗焦虑的作用。
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LY404039
CAS number：635318-11-5 molecular formula：C7H9NO6S
overview
Specs
| Chinese alias | - | ||
| English alias | (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide | ;(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide | LY404039 | LY-404039 | UNII-531QUG7P9E | rel-(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1 | ||
| CAS number | 635318-11-5 | molecular formula | C7H9NO6S |
| molecular weight | 235.21 g/mol | Exact mass | 2mM in DMSO |
| PSA | 143.000 Ų | logp | -4.8 |
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