SCH-900271 是一种 烟酸受体 (NAR) 激动剂,在 hu-GPR109a 测定中 EC50 为 2 nM。SCH-900271 对血浆游离脂肪酸 (FFA) 具有剂量依赖性抑制作用。SCH-900271 改善了潮红治疗窗口。 SCH-900271 is potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA). SCH-900271 has an improved therapeutic window to flushing.
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SCH 900271
CAS number:915210-50-3 molecular formula:C14H16N2O4
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| Chinese alias | SCH900271 | ||
| English alias | SCH900271 | SCH-900271 | 5-[3-(1-Methylcyclopropyl)propyl]-2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-trione | DTXSID00238609 | SB17408 | G2283XQ6VJ | DB12433 | 2H-Pyrano(2,3-d)pyrimidine-2,4,7(1H,3h)-trione, 5-(3-(1-methylcyclopropyl)propyl)- | GTPL8469 | S | ||
| CAS number | 915210-50-3 | molecular formula | C14H16N2O4 |
| molecular weight | 276.29 g/mol | Exact mass | - |
| PSA | - | logp | - |
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