Ralmitaront (RO6889450) 是一种微量胺相关受体 1 (TAAR1) 的激动剂,EC50 值为 110.4 nM。Ralmitaront 在啮齿动物中具有抗精神病、认知改善和抗抑郁的活性。Ralmitaront 可作为一种神经抑制剂,用于神经相关疾病的研究,如精神分裂症 (SCZ)、分裂情感性障碍。 Ralmitaront (RO6889450) is an agonist of trace amine-associated receptor 1 (TAAR1) with a EC50 value of 110.4 nM. Ralmitaront has antipsychotic, cognitively improvement, and antidepressant activity in rodents. Ralmitaront can be used as a neurosuppressant in the study of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder .
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Ralmitaront
CAS number:2133417-13-5 molecular formula:C17H22N4O2
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| Chinese alias | 雷米塔隆 | ||
| English alias | (s)-5-ethyl-4-methyl-n-(4-(morpholin-2-yl)phenyl)-1h-pyrazole-3-carboxamide | 5-Ethyl-4-methyl-N-{4-[(2S)-morpholin-2-yl]phenyl}-1H-pyrazole-3-carboxamide | 5-Ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]-1H-pyrazole-3-carboxamide | DTXSID901336976 | ||
| CAS number | 2133417-13-5 | molecular formula | C17H22N4O2 |
| molecular weight | 314.38 g/mol | Exact mass | - |
| PSA | 79.000 Ų | logp | 1.600 |
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