compound introduction
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with K i of 33 μM. In Vitro MRZ 2-514 has IC 50 values against peak AMPA-induced currents of 72.7 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Ki: 33 μM (glycineB)
