CAS number：1807512-46-4 molecular formula：C23H26F5NO9
Mal-PEG5-PFP ester 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。 Mal-PEG5-PFP is a PEG derivative containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
| Chinese alias | 1-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)-3,6,9,12,15-五氧杂十八烷-18-酸全氟苯基酯 | ||
| English alias | Perfluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate | Mal-PEG5-PFP ester | ||
| CAS number | 1807512-46-4 | molecular formula | C23H26F5NO9 |
| molecular weight | 555.45 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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