compound introduction
Selamectin，一种半合成的大环内酯，是一种抗寄生虫剂和驱虫剂。Selamectin 激活神经元和咽肌中的谷氨酸门控氯离子通道 (glutamate-gated chloride channels)，以预防恶丝虫，淋巴丝虫和线虫感染。Selamectin 还是一种有效的 P-糖蛋白 (P-glycoprotein) 底物和抑制剂，IC50 为 120 nM。
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Selamectin
Dangerous GoodsCAS number：220119-17-5 molecular formula：C43H63NO11
overview
Specs
| Chinese alias | 司拉克丁 | 塞拉菌素 | ||
| English alias | CAS-165108-07-6 | Selamectin (USAN/INN) | STRONGHOLD PLUS COMPONENT SELAMECTIN | (1R,4S,5'S,6R,6'S,8R,10E,12S,13S,14E,16E,20R,21Z,24S)-6'-cyclohexyl-24-hydroxy-21-hydroxyimino-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetrame | ||
| CAS number | 220119-17-5 | molecular formula | C43H63NO11 |
| molecular weight | 769.96 g/mol | Exact mass | ≥97% |
| PSA | 155.000 Ų | logp | 5.400 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS09
Signal word：
Warning
Hazard Statement：
H400: 对水生生物有剧毒 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P391: 收集溢出物 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。
Production methods and uses
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Related
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downstream information
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MSDS
Found 1 shareMSDS
220119-17-5 | Selamectin, UNITED STATES PHARMACOPEIA(USP) REFERENCE STANDARD.pdf
