SAG dihydrochloride 是一种有效的 Smoothened (Smo) 受体激动剂 (EC50=3 nM; Kd=59 nM)。SAG dihydrochloride 可激活 Hedgehog 信号通路并抵消 Cyclopamine (HY-17024) 对 Smo 的抑制作用。 SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo
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SAG dihydrochloride
CAS number:2702366-44-5 molecular formula:C28H30Cl3N3OS
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| Chinese alias | SAG 二盐酸盐 | ||
| English alias | - | ||
| CAS number | 2702366-44-5 | molecular formula | C28H30Cl3N3OS |
| molecular weight | 562.98 g/mol | Exact mass | - |
| PSA | - | logp | - |
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