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(S)-5-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

CAS number:1258494-60-8    molecular formula:

overview

compound introduction

TH1338 (compound 3b) 是具有口服活性的喜树碱的衍生物,是有潜力的抗癌化合物,在体外表现出优异的肿瘤细胞毒性的效果。TH1338 (compound 3b) 具有显著的血脑屏障透过性,良好的外排泵特性和低血液学毒性。

Specs

Chinese alias-
English alias-
CAS number1258494-60-8molecular formula
molecular weight391.400 g/molExact mass≥98%
PSA106.000 Ųlogp0.800

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