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MC-VC-PABC-C6-alpha-Amanitin

CAS number:2922514-69-8    molecular formula:C74H105N17O22S

overview

compound introduction

MC-VC-PABC-C6-α-Amanitin 是一种抗体活性分子偶联物 (ADC),由抗癌毒素 α-Amanitin和单克隆抗体 MC-VC-PABC-C6 组成。其中 α-Amanitin 是强效的 RNA 聚合酶 IIα 抑制剂。MC-VC-PABC-C6-α-Amanitin 可准确靶向 HER2 受体,特异性识别 HER2 阳性的肿瘤细胞,广泛用于乳腺癌和胃癌研究。 MC-VC-PABC-C6-α-Amanitin is an antibody agent conjugate consisting of an anticancer toxin alpha-Amanitin and a monoclonal antibody MC-VC-PABC-C6. Among them, alpha-Amanitin is a potent inhibitor of RNA polymerase IIα. MC-VC-PABC-C6-α-Amanitin accurately targets HER2 receptors, specifically recognizes HER2-positive tumor cells. It is widely used in breast cancer and gastric cancer research.

Specs

Chinese alias-
English alias-
CAS number2922514-69-8molecular formulaC74H105N17O22S
molecular weight1616.79 g/molExact mass≥98%
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