心磷脂是一种独特的磷脂，位于线粒体内膜 ，占总脂质的 20%。心磷脂是一种具有四个酰基链和一个小分子头基的非双层阴离子磷脂。 心磷脂是一种阴离子磷脂。 心磷脂有两个通过甘油连接的磷脂酰残基。18:1 心磷脂或四油酰心磷脂 (TOCL) 是一种单不饱和的线粒体磷脂。TOCL 的双层厚度高于心脏心磷脂。与二油酰磷脂酰胆碱 (DOPC) 双层膜相比，TOCL 双层膜具有更大的烃链厚度。 用途： 18:1 心磷脂已被用于： 制备纯 (100%) 心磷脂囊泡 用发光分析法测细胞色素 c 过氧化物酶活性的强度 测固定在生物传感器芯片中的细胞色素 c Trp59 的荧光 研究细胞色素 c 与阴离子磷脂的缔合 18:1 心磷脂已被用作鲁米诺增强化学发光的脂质底物。 18:1 心磷脂已用于： 制备脂质体，用于重构细菌的力学敏感通道 固定在亲脂性生物传感器 L1 芯片表面上 作为过氧化物酶氧化试验中的脂质底物 Cardiolipin, the mitochondrial-specific phospholipid, helps maintain mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and the proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy (Barth syndrome). Cardiolipin has also been shown as a signaling molecule in apoptosis.
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1',3'-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol (sodium salt)
CAS number：115404-77-8 molecular formula：C81H148O17P2Na2
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compound introduction
Specs
| Chinese alias | 18:1 心磷脂 | 四油酰心磷脂 | 1,1',2,2'-四-(9Z-十八碳烯酰)心磷脂(钠盐) | ||
| English alias | - | ||
| CAS number | 115404-77-8 | molecular formula | C81H148O17P2Na2 |
| molecular weight | 1501.959 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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MSDS
Found 1 shareMSDS
1 ', 3' -di [1,2-hexadiene-sn-propanetrioxy-3-phosphate] -sn-glycerol (sodium salt) preparation solution | 1 ', 3' -bis [1,2-dioleoyl-sn-glycero-3-phospho] -glycerol (sodium salt)
