Emricasan (IDN-6556, PF 03491390, PF-03491390)是有效的、不可逆的泛半胱天冬酶(pan-caspase)抑制剂。Emricasan 也是寨卡病毒感染的抑制剂。 Emricasan (PF 03491390) 是一种有效的 不可逆 pan-caspase 抑制剂。Emricasan 抑制 Zika 病毒 (ZIKV) 诱导的 caspase-3 活性增加并保护了人类皮层神经祖细胞。
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Emricasan
CAS number:254750-02-2 molecular formula:C26H27F4N3O7
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | (S)-3-((S)-2-(2-(2-TERT-BUTYLPHENYLAMINO)-2-OXOACETAMIDO)PROPANAMIDO)-4-OXO-5-(2,3,5,6-TETRAFLUOROPHENOXY)PENTANOIC ACID | VAY-785 | HMS2425L14 | Emricasan (IDN-6556, PF-03491390) | Emricasan [USAN:INN] | DB05408 | PF-03491390 | (3S)-3-[[(2S)-2-[[2-(2-ter | ||
| CAS number | 254750-02-2 | molecular formula | C26H27F4N3O7 |
| molecular weight | 569.51 g/mol | Exact mass | - |
| PSA | 151.000 Ų | logp | 3.6 |
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